高 威 副教授

发布时间:2024-03-01

高威.jpg


高威,副教授


电子邮箱:wgao@hsc.ecnu.edu.cn


教育经历:

1996/09-2000/07       天津科技大学学士/本科

2000/09-2003/07       南开大学硕士/研究生

2005/07-2010/11       香港大学博士/研究生


工作经历:

2011/08-2015/08   香港大学李嘉诚医学院博士后

2016/10-2021/04   香港大学李嘉诚医学院助理教授(研究)

2021/10-2022/09   香港中文大学科比尔卡创新药物开发研究院研究员

2022/09-至今华东师范大学医学与健康研究院副教授


研究领域:

结构药理学:依据结构的G蛋白偶联受体(GPCR)药物研发

肿瘤药理学:靶向GPCR的抗肿瘤药物开发


学术团体任职:

Frontiers in Oncology杂志编委

中国抗癌协会会员

美国癌症研究协会会员

Frontiers in Oncology, Frontiers in Genetics, PLOS ONE, Pathology-Research and Practice等杂志审稿人


科研项目:

主持国家自然科学基金面上项目、上海市浦江人才计划、医疗卫生研究基金(HMRF,香港)、余兆麟医疗基金(香港)等。


文章发表:

1.Gao W, Hu L, Zhang M, Liu S, Xu S, Chow VL, Chan JY, Wong TS. Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC. Am J Cancer Res. 2022 Jan 15;12(1):48-67

2.Gao W, Xu S, Zhang M, Liu S, Siu SP, Peng H, Ng JC, Tsao GS, Chan AW, Chow VL, Chan JY, Wong TS. NADPH oxidase 5α promotes the formation of CD271 tumor-initiating cells in oral cancer. Am J Cancer Res. 2020 Jun 1;10(6):1710-1727.

3.Zhang M*, Gao W*, Liu S, Siu SP, Yin M, Ng JC, Chow VL, Chan JY, Wong TS. CD38 triggers inflammasome-mediated pyroptotic cell death in head and neck squamous cell carcinoma. Am J Cancer Res. 2020;10(9):2895-2908. *Equal contributors

4.Gao W, Li JZ, Chen SQ, Chan JY, Yin M, Zhang MJ, Wong TS. Epstein-Barr virus encoded microRNA BART7 regulates radiation sensitivity of nasopharyngeal carcinoma. Oncotarget. 2017;8(12):20297-20308.

5.Wong TS, Li JZ, Chen SQ, Chan JY, Gao W*. The Efficacy of Triamcinolone Acetonide in Keloid Treatment: A Systematic Review and Meta-analysis. Front Med (Lausanne). 2016;3:71. *Corresponding author

6.Gao W, Li JZ, Chen SQ, Chu CY, Chan JY, Wong TS. Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma. J Exp Clin Cancer Res. 2016;35(1):92.

7.Wei FQ, Sun W, Wong TS, Gao W, Wen YH, Wei JW, Wei Y, Wen WP. Eliciting cytotoxic T lymphocytes against human laryngeal cancer-derived antigens: evaluation of dendritic cells pulsed with a heat-treated tumor lysate and other antigen-loading strategies for dendritic-cell-based vaccination. J Exp Clin Cancer Res. 2016;35(1):18.

8.Gao W, Shi Y, Liu W, Lin WY, Wu JC, Chan JY, Wong TS. Diagnostic value of methylated human telomerase reverse transcriptase in human cancers: A meta-analysis. Front Oncol. 2015;5:296.

9.Gao W, Chan JY, Wong TS. Curcumin exerts inhibitory effects on undifferentiated nasopharyngeal carcinoma by inhibiting the expression of miR-125a-5p. Clin Sci (Lond). 2014;127(9):571-9.